Combined mutation spectrum

These plots shows the total number of observations in each subtype, combined across all samples

All samples

Signature loadings (H matrix)

Describes how each mutation subtype is loaded into the r signatures

## # A tibble: 3 x 4
##   rowname        S1        S2        S3
##     <chr>     <dbl>     <dbl>     <dbl>
## 1      S1        NA 0.9783121 0.8396949
## 2      S2 0.9783121        NA 0.7716099
## 3      S3 0.8396949 0.7716099        NA

Signature contributions per sample (W matrix)

Proportion each signature contributes to the mutation spectrum in each individual sample

Interactive heatmap of error profiles

IDs with similar error profiles are grouped together using hierarchical clustering.

Error profiles for top 20 outliers